Five players went down with a sickness bug with midfielders Darren Ambrose and Neil Danns the worst affected.
Ambrose could only manage to play the first half as Palace went down 2-0 at Bramall Lane, and he and Danns did not train in the earlier part of this week and will be checked over.
Defender Paddy McCarthy remains the only long-term injury absentee, the Irish defender not due back until March following shoulder surgery last month.
Boss Neil Warnock must decide who out of Freddie Sears, Alan Lee and Calvin Andrew will partner teenage frontman Victor Moses, who has been linked with a move to the Premier League in January.
Barnsley manager Mark Robins faces a selection dilemma over fit-again skipper Stephen Foster for the clash.
Foster missed the 2-2 home draw with Newcastle last week due to a cut eye that required six stitches but the defender is back in contention for Selhurst Park.
Bobby Hassell, back to full fitness himself following an Achilles problem, returned to the starting line-up against Newcastle and capped an impressive display with an 87th-minute equaliser, so he will be hoping to retain his place.
Robins, who has no other new injury or suspension problems, will be loathe to make too many, if any, changes to his side.
Barnsley turned in one of their best displays under Robins in the second half against Newcastle and are aiming to extend their unbeaten league run to seven matches.
Sporting Life