QPR goalkeeper Radek Cerny, who has not played for the first team since January, is set to return because Carl Ikeme's loan spell has now finished.
Dusko Tosic is being considered for a debut at left-back, but Matt Connolly (ankle) is still struggling.
As if Neil Warnock's return to Selhurst Park was not already guaranteed to be spicy enough, QPR's recent run of results makes this a crucial relegation showdown.
The west London side are without a win in seven matches and their Easter Monday mauling by play-off chasers Leicester means they remain in serious danger of falling into League One.
It also means that Crystal Palace, the club Warnock controversially quit to take over at Rangers just over a month ago, will go above them if they win Saturday's derby. It could also leave QPR above the bottom three only on goal difference, depending on other results.
Eagles boss Paul Hart, who had a five-game spell as R's manager earlier in the season, described Palace's 3-1 victory against Preston as "massive." It was their second win in three matches and lifted them out of the relegation zone.
• QPR have won 30 and Palace 29 of the 85 previous league meetings between these clubs. The last three have ended in draws.
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• Palace are unbeaten in six matches against Rangers (W2, D4).
• The R's have won only one of their last 13 matches against Palace and the club's last victory over them at Selhurst Park was a 3-0 triumph in December 1989. It was Ray Wilkins' QPR debut.
• Palace, who have picked up seven points out of nine, would be three places outside the play-off zone had they not been docked 10 points after going into administration.
• The Eagles have won 14, drawn 14 and lost 14 of their 42 league games, scoring 46 goals and gaining 46 points.
Queens Park Rangers
• QPR have taken only five points from a possible 21 since winning their first two matches under Neil Warnock.
• They have squandered 24 points from winning positions this season - more than any other team in the Championship.
• Peter Ramage could make his 100th career league start, while Mikele Leigertwood is set to face his former club.
MOST RECENT MEETING
QPR 1-1 Crystal Palace (3 November 2009)
QPR scorer: Buzsaky (pen) 19.
Palace scorer: Ambrose (pen) 62.
Source: BBC Sport
Source: BBC Sport