Sheffield United forward Richard Cresswell could miss out with a knee problem, while Ched Evans is also a doubt as he has a virus.
Nick Montgomery, Chris Morgan, Andy Taylor, Ryan France, Darius Henderson and goalkeeper Richard Wright are among those already sidelined.
MATCH PREVIEW
Relegation-threatened Crystal Palace and Sheffield United meet in a proverbial six-pointer at Selhurst Park, where neither side can afford to lose Saturday's crunch match.
Palace have won only once since Dougie Freedman was given the manager's job. But they have climbed out of the bottom three and been replaced by United, the team immediately below them, who are yet to win since the appointment of Micky Adams as Blades boss.
The Yorkshire side have drawn their last two league matches and have gone 10 without a victory. Since beating Swansea a week before Christmas, United have picked up a paltry four points and desperately need to turn their fortunes around.
Palace's last home game was another vital match against a fellow struggling team, Middlesbrough. They won that, and their home form could be the key to their Championship survival. Of their 31 points, only six have been secured away.
MATCH FACTS
Head-to-head
• This is the 50th league meeting of these clubs. Crystal Palace have won 19 of the previous 49 - one more than Sheffield United.
Crystal Palace
• A draw for Palace would be the club's 500th at home in the league.
• The Eagles have won only two of their last 12 league matches and this season are averaging a point per game, having taken 31 points from 31 outings.
• They have drawn three and lost two of their six league games since Dougie Freedman was given the manager's job.
• Palace have won one of their last seven matches
• David Wright is in line for his 400th league appearance, and Darren Ambrose his 250th.
Sheffield United
• This is United's 900th away match in the second tier.
• The Blades have drawn four and lost five of their nine league and cup games since Micky Adams took charge.
• On-loan striker Marcus Bent could face one of his former clubs.
Source: BBC Sport
Source: BBC Sport