Right-back Clyne was this week ruled out of the England Under-20 clash with France due to a knee injury and is set to lose his ever-present record this season.
Midfielder Danns is still struggling with the back problem which sidelined him for last Saturday's win over Middlesbrough and manager Dougie Freedman rates him doubtful.
David Wright, who moved into the midfield in Danns' absence, could now drop back into the defence to fill in for Clyne.
Striker James Vaughan will lead the line again after playing an hour for England's Under-21s in midweek.
Full-back Lee Hills remains a long-term absentee with a knee injury.
Source: PA
Source: PA