Palace are looking for a third straight win and will fancy their chances against Simon Davey's side but the Tykes are on a high after a 4 - 1 win in their last game against Doncaster Rovers.
Paddy McCarthy and Matt Lawrence are pushing to be fit in time for the game.
Irish centre-half McCarthy has been given the green light to be involved by a specialist after dislocating his shoulder at Nottingham Forest a fortnight ago.
Fellow defender Lawrence had an injection in his groin following the Forest game and is also back in training.
Striker Alan Lee is another player on the mend following a hamstring injury, but manager Neil Warnock is likely to hold him back until Tuesday's trip to Birmingham after rushing him back too soon previously.
Calvin Andrew (knee) is also close to returning, although Saturday is just too early, and James Scowcroft (hamstring) is a fortnight away.
Barnsley will be without suspended defender Darren Moore.
The imposing centre-half was sent off for a professional foul in the recent win over Doncaster and now serves a one-game ban.
Stephen Foster is expected to move across to play in central defence alongside Dennis Souza, while Bobby Hassell provides manager Simon Davey with an option at right-back.
Hugo Colace will return to his defensive midfield role after missing the last match with an ankle injury.
The Argentinian will line-up alongside Diego Leon, Anderson De Silva and Jamal Campbell-Ryce, who is hoping to return from international duty with Jamaica in time to start.
Campbell-Ryce was outstanding in both the Reggae Boyz' 1-0 World Cup qualifying wins over Mexico and Honduras.