Palace hope to welcome back a couple of key players as they aim to breathe new life into their belated play-off push.
Wednesday's last gasp win at West Brom has given the Eagles cause for renewed optimism, though the play-off spots are still a distant eight points away.
Their cause should be helped by the return to fitness of Shekfi Kuqi and Mark Kennedy - both of whom have taken part in full training this week.
However, wingers Paul Ifill and Jobi McAnuff are still ruled out.
Plymouth could be much changed after a dismal 4-2 home defeat by Barnsley during midweek.