Boss Stuart Pearce has turned to the on-loan Everton forward for Tuesday's clash with Italy in Tuscany after being hit with a host of injuries.
Vaughan has scored twice since he returned to Selhurst Park last month, including the winner in Saturday's 1-0 victory over Middlesbrough.
Meanwhile, Palace defender Nathaniel Clyne has pulled out of the England Under-20 squad to play France on Wednesday due to injury.
Source: PA
Source: PA